Why is RWE becoming a critical asset for market leaders?
Clinical trials for rare diseases like GIST often have small sample sizes. This can make payers skeptical of the broad clinical benefit. Real-World Evidence (RWE)—data collected from actual clinical practice—fills this gap by showing how the drug performs in a more diverse, "real-world" patient population over longer periods.
How is GIST Real-World Data Utilization shaping 2024 HTA?
In 2024, GIST Real-World Data Utilization is being used to support Health Technology Assessment (HTA) submissions in Europe. By demonstrating that a new fourth-line agent reduces hospitalizations and emergency room visits, manufacturers can justify a higher price point. For consultants, RWE is now a mandatory component of the "Value Dossier."
What is the role of AI in RWE by 2025?
By 2025, AI-driven platforms will be able to scan Electronic Health Records (EHRs) to identify GIST patients who are about to fail their current therapy. This predictive RWE allows pharmaceutical companies to reach out to physicians at the exact moment a treatment change is needed, optimizing the clinical intervention cycle.
- Bridging the gap between Phase III trials and clinical practice.
- Identifying "long-term responders" to understand drug durability.
- Providing data for label expansions into rare GIST subtypes.
2025 RWE Outlook
The 2025 outlook indicates that RWE will be used to secure "conditional reimbursement." Payers may agree to cover a drug based on trial data, but continue coverage only if RWE confirms the benefits in the first 1,000 patients treated, creating a "live" pricing model for new innovations.
Author: Sofiya Sanjay
Designation: Healthcare Research Consultant, Market Research Future
About: At Market Research Future (MRFR), we enable organizations to unravel complex industries through Cooked Research Reports (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services. Our studies across products, technologies, applications, end users, and global to country-level segments help decision-makers see more, know more, and do more.
Contact: 99 Hudson Street, 5th Floor, New York, NY 10013, USA | (855) 661-4441 (US) | +44 1720 412 167 (UK) | +91 2269738890 (APAC) | info@marketresearchfuture.com